Locally advanced rectal cancer patients may not need radiotherapy

New data from US researchers indicates some patients with locally advanced rectal cancer with tumours that respond to chemotherapy can safely forego radiation before surgery.

Omitting radiation therapy from these patients’ treatment plan can reduce short- and long-term side effects while providing similar outcomes in disease-free survival and overall survival.

The research, led by Memorial Sloan Kettering Cancer Center (MSK) and Dana-Farber Brigham Cancer Center featured in the 2023 American Society of Clinical Oncology (ASCO) Annual Meeting press program and was simultaneously published in The New England Journal of Medicine(NEJM) and the Journal of Clinical Oncology.

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